A Target Sequential Effect on the Forced-Choice Prime Visibility Test in Unconscious Priming Studies: A Caveat for Researchers

In unconscious priming studies, most researchers adopt a combination of subjective and objective measures to assess the visibility of the prime. Although some carry out the visibility test at the end of the experiment separately from the unconscious priming task, others suggest that the forced-choice visibility test should be conducted immediately after the response to the target within each trial. In the present study, the influence of prime and target on the forced-choice prime discrimination was assessed within each trial. The results showed that the target affected the response in the forced-choice prime visibility test. Participants tended to make the same response or avoid repeating the same response they made to the target as in Experiments 1 and 3 rather than randomly guessing. However, even when the forcedchoice visibility test was conducted separately from the priming experiment, the problem was not completely solved, because some participants tended to make one same response in the forced-choice visibility test as in Experiments 2. From another point of view, using these strategies in the forced-choice task can be seen as a helpless move by the participants when they are unaware of the stimuli. Furthermore, the results revealed that the forced-choice test performed immediately after the response to the target within each trial could possibly impair the unconscious priming as well as produce misleading visibility test results. Therefore, it is suggested that the forced-choice prime visibility test and the unconscious priming task may better be conducted separately

Chloride Ion Penetration Resistance of Reactive Powder Concrete with Mineral Admixtures

This study employed the rapid chloride ion penetration test and the salt spray erosion method to examine electric flux changes in mineral-admixed reactive powder concrete (RPC). Variations in the chloride ion content and diffusion coefficient under different erosion durations and depths were also investigated. The impact of mineral admixtures on the chloride penetration resistance was explored. Notably, after mixing fly ash (FA) and granulated blast furnace slag (GGBS), the electric flux values of RPC of each group were significantly reduced, and the electric flux values of RPC of the mixed group were significantly lower than those of the single mixed group and the reference group, in which the electric flux of FA10G10 was reduced by 85.2% compared to the control group; at the same erosion cycle and depth, the chloride ion content and diffusion coefficient of the mixed group were significantly lower than the control group. It shows that the reasonable compounding of mineral admixtures can better exert the "superposition effect", improve the compactness inside the matrix, and effectively reduce the chloride ion penetration rate. Considering comprehensively, the FA10G10 group has the best chloride penetration ion resistance effect

Diptoindonesin G is a middle domain HSP90 modulator for cancer treatment

HSP90 inhibitors can target many oncoproteins simultaneously, but none have made it through clinical trials due to dose-limiting toxicity and induction of heat shock response, leading to clinical resistance. We identified diptoindonesin G (dip G) as an HSP90 modulator that can promote degradation of HSP90 clients by binding to the middle domain of HSP90 (

Omnichannel Retail Strategy Considering Cost-Sharing and Consumer Heterogeneity under Different Power Structures

This paper explores two Omnichannel retail models consisted of one online platform and one brick-and-mortar store under different power structures considering cost-sharing mechanisms. In retail supply chain dominated by the online platform and brick-and-mortar store, respectively, under a “Buy online and pick up in store” strategy, the influences of the cost-sharing ratio and the proportion of traditional consumers on pricing and service decisions, the demands of various groups of consumers, and the performance of the retail system have been examined. In addition, the results of decision-making and profitabilities of retailers under different power structures have also been considered. The key findings show that the optimal price and service level first increase and then decrease with the cost-sharing ratio in a retail system dominated by the online platform. In contrast, the price and service level increase with the cost-sharing ratio only when the proportion of traditional consumers is relatively large in a retail system dominated by brick-and-mortar store. The symmetry demand increases as the scale of traditional consumers shrinks when the cost-sharing ratio is relatively large in a retail system dominated by the online system. At the same time, it only increases when the cost-sharing ratio is in the range of 5/8,5/6 in a retail system dominated by the brick-and-mortar store. No matter what the power structure is, the profit of the retail system always first increases and then decreases with the proportion of traditional consumers. Additionally, when the cost-sharing ratio and the proportion of traditional consumers are relatively small, the total demand in the retail system dominated by the online platform is higher than that in the retail system dominated by the brick-and-mortar store. The total profit is larger in the online platform-dominated retail system than that in the brick-and-mortar store-dominated retail system when the cost-sharing ratio is relatively high. However, when the cost-sharing ratio is relatively low, the profitability of the brick-and-mortar store-dominated retail system is stronger

Omnichannel Retail Strategy Considering Cost-Sharing and Consumer Heterogeneity under Different Power Structures

This paper explores two Omnichannel retail models consisted of one online platform and one brick-and-mortar store under different power structures considering cost-sharing mechanisms. In retail supply chain dominated by the online platform and brick-and-mortar store, respectively, under a “Buy online and pick up in store” strategy, the influences of the cost-sharing ratio and the proportion of traditional consumers on pricing and service decisions, the demands of various groups of consumers, and the performance of the retail system have been examined. In addition, the results of decision-making and profitabilities of retailers under different power structures have also been considered. The key findings show that the optimal price and service level first increase and then decrease with the cost-sharing ratio in a retail system dominated by the online platform. In contrast, the price and service level increase with the cost-sharing ratio only when the proportion of traditional consumers is relatively large in a retail system dominated by brick-and-mortar store. The symmetry demand increases as the scale of traditional consumers shrinks when the cost-sharing ratio is relatively large in a retail system dominated by the online system. At the same time, it only increases when the cost-sharing ratio is in the range of 5/8,5/6 in a retail system dominated by the brick-and-mortar store. No matter what the power structure is, the profit of the retail system always first increases and then decreases with the proportion of traditional consumers. Additionally, when the cost-sharing ratio and the proportion of traditional consumers are relatively small, the total demand in the retail system dominated by the online platform is higher than that in the retail system dominated by the brick-and-mortar store. The total profit is larger in the online platform-dominated retail system than that in the brick-and-mortar store-dominated retail system when the cost-sharing ratio is relatively high. However, when the cost-sharing ratio is relatively low, the profitability of the brick-and-mortar store-dominated retail system is stronger

Sexual Orientation Identity Change, Developmental Trajectories of Depressive Symptoms, and Childhood Abuse from Adolescence to Young Adulthood

Purpose: This study tested differences between youths who reported being heterosexual at ages 15.5 and 21, and those who changed from reporting being heterosexual at age 15.5 to nonheterosexual at age 21, in the developmental trajectories of depressive symptoms from age 22–24 years, and whether these longitudinal patterns were explained by childhood and adolescent abuse. Methods: The Avon Longitudinal Study of Parents and Children (ALSPAC) was used (849 male youths and 1,455 female youths). Youths' self-reported sexual orientation was measured at ages 15.5 and 21, and depressive symptoms were measured at ages 22, 23, and 24. Childhood and adolescent abuse between birth and 17 years were reported by youths and their mothers. Results: Male and female youths who changed from reporting being heterosexual to nonheterosexual reported significantly more depressive symptoms than their consistently heterosexual counterparts at all 3 ages (except the association for male youths at age 24), with total effects (unstandardized regression coefficients) ranging from 2.00 to 5.27. These associations were weakened but remained statistically significant when childhood and adolescent abuse was controlled for, with direct effects ranging from 1.50 to 4.68. These associations were mediated through childhood and adolescent abuse, with indirect effects ranging from 0.48 to 0.58. Differences between youths who consistently reported being heterosexual and those who changed from reporting being heterosexual to nonheterosexual in depressive symptoms decreased from age 22–24 years, possibly due to the success of identity integration. Discussion: Childhood and adolescent abuse may partially explain these developmental disparities.</p